Tendon stem cells: experimental and clinical perspectives in tendon and tendon-bone junction repair

Po Yee Lui, Pauline and Wong, On Tik (2012) Tendon stem cells: experimental and clinical perspectives in tendon and tendon-bone junction repair. M.L.T.J. Muscles, Ligaments and Tendons Journal, 2 (3). pp. 163-168. ISSN 2240-4554

Preview

PDF article.pdf - Published Version Download (789kB)

Abstract

Tendon and tendon-bone junction injuries, while heal, have high re-tear rates. Mesenchymal stem cells (MSCs) have great appeal for the promotion of tendon and tendon-bone junction healing because of their high proliferation rate, multi-potency and relative ease of isolation from various tissues. Tendon stem cells have been identified recently and could be an alternative new cell source for tendon and tendonbone junction repair. In this review, we summarized the in vitro characteristics of tendon stem cells. The evidence supporting the potential use of these cells for tendon and tendon-bone junction repair was presented. In order to therapeutically apply tendon stem cells in the clinical settings, standardization of tendon stem cell culture is essential. Issues relating to the sources, purity, efficacy, safety and delivery of tendon stem cells for tendon and tendon-bone junction repair were summarized and discussed. The direction for future research was suggested

Item Type:	Article
Uncontrolled Keywords:	Tendon stem cells, tendon progenitors, tendon healing, tendon-bone junction healing, tissue engineering
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User:	Danilo Dezzi
Date Deposited:	16 Apr 2014 16:14
Last Modified:	16 Apr 2014 16:14
URI:	http://eprints.bice.rm.cnr.it/id/eprint/8134

Actions (login required)

View Item