Pulmonary immune response to Streptococcus pneumoniae

Periselneris, Jimstan and José, Ricardo J. and Brown, Jeremy S. (2014) Pulmonary immune response to Streptococcus pneumoniae. Shortness of Breath, 3 (4). pp. 147-158. ISSN 2281-6550


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Streptococcus pneumoniae is a common cause of respiratory infection associated with significant morbidity and mortality. The immune response to S. pneumoniae is complex, multi-layered and incompletely understood. The lung has non-specific defence mechanisms that include cellular and secreted components. The initial response to bacteria that adhere to or breach the epithelium is mediated by the innate immune system and recognition of non-specific motifs common to many pathogens. This stimulates the inflammatory response and subsequently the development of the more specific adaptive immune system. Better understanding of the immune response to S. pneumoniae will underpin future progress in both the prevention of infection and adjuvants to existing treatments.

Item Type: Article
Uncontrolled Keywords: Streptococcus pneumoniae; immunology
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 21 Jan 2016 17:31
Last Modified: 21 Jan 2016 17:31
URI: http://eprints.bice.rm.cnr.it/id/eprint/10525

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