Two cases of cluster headache effectively treated with levetiracetam

Palermo, Antonio and Giglia, Giuseppe and Cosentino, Giuseppe and Raieli, Vincenzo and Brighina, Filippo and Fierro, Brigida (2013) Two cases of cluster headache effectively treated with levetiracetam. Functional Neurology, 28 (1). pp. 63-64. ISSN 1971-3274

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Cluster headache (CH), which is characterized by recurrent attacks of short-lasting excruciating pain accompanied by signs of autonomic dysfunction (ICHD-II) (Headache Classification Subcommittee of the IHS, 2004), is the most severe of the primary headache syndromes. CH is the most common of the trigeminal autonomic cephalalgias (TACs), whose pathophysiology has not been completely elucidated (Leone and Bussone, 2009). The treatment of CH is still debated. Verapamil (a calcium antagonist) and lithium are the first-option drugs. Several drugs have been proposed as alternative treatments, but only some of these showed limited efficacy. Recently, a new-generation antiepileptic drug, topiramate (200 mg/day), was reported to ameliorate CH (Leone et al., 2003). Here we describe two cases of CH that became unresponsive to classical treatment and were effectively treated with levetiracetam (LEV).

Item Type: Article
Additional Information: Letter to the editor
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 17 Dec 2015 15:03
Last Modified: 17 Dec 2015 15:03

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