Differences between conventional and non-conventional MRI techniques in Parkinson’s disease

Baglieri, Annalisa and Marino, Maria Adele and Morabito, Rosa and Di Lorenzo, Giuseppe and Bramanti, Placido and Marino, Silvia (2013) Differences between conventional and non-conventional MRI techniques in Parkinson’s disease. Functional Neurology, 28 (2). pp. 73-82. ISSN 1971-3274

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Magnetic resonance imaging (MRI) provides an in vivo assessment of cortical and subcortical regions affected in Parkinson’s disease (PD). This review summarizes the most important conventional and non-conventional MRI techniques applied in this field. Standard neuroimaging techniques have played a marginal role in the diagnosis and follow-up of PD, essentially being used only to discriminate atypical syndromes from PD, to exclude secondary causes such as vascular lesions, and to confirm the absence of specific imaging features found in atypical parkinsonisms. However, non-conventional MRI techniques, i.e. new neuroimaging approaches such as magnetic resonance spectroscopy, diffusion tensor imaging, and functional MRI, may allow the detection of structural, functional and metabolic changes useful not only for differential diagnosis, but also for early diagnosis and outcome and treatment monitoring in PD. In addition, we illustrate the advantages of high-field MRI over lower magnetic fields, highlighting the great potential of advanced neuroimaging techniques.

Item Type: Article
Uncontrolled Keywords: diffusion tensor imaging, functional magnetic resonance imaging, high-field MRI, magnetic resonance spectroscopy, Parkinson’s disease, volumetric MRI
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 17 Dec 2015 14:46
Last Modified: 17 Dec 2015 14:46
URI: http://eprints.bice.rm.cnr.it/id/eprint/10813

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