Non-genetic factors associated with the risk of Parkinson’s disease in Iranian patients

Hosseini Tabatabaei, Narges and Babakhani, Babak and Hosseini Tabatabaei, Azadeh and Vahabi, Zahra and Soltanzadeh, Akbar (2013) Non-genetic factors associated with the risk of Parkinson’s disease in Iranian patients. Functional Neurology, 28 (2). pp. 107-113. ISSN 1971-3274

article.pdf - Published Version

Download (544kB) | Preview
Official URL:


The aim of this study was to investigate some of non-genetic factors associated with Parkinson’s disease (PD) in a sample of Iranian patients. This case-control study included 75 patients with idiopathic PD and 75 control patients. The patients in the control group were found to have drunk more glasses of tea per day than the case group before the onset of their problem (p=0.019). Every extra glass of tea per day decreased the risk of PD by 0.8 times (OR=0.8, 95%CI=0.73-0.97, p=0.02). Each cup of coffee per week decreased the chance of developing PD by 0.5 times (OR=0.5, 95%CI=0.28-0.9, p=0.021). A previous history of evening work increased PD risk by 4.6 times (OR=4.6, 95%CI=1.29-16.86, p=0.019) while major stressful events increased it by 13.5 times (OR=13.5, 95%CI=4.7-38.1, p=0.0001). In conclusion, coffee and tea consumption may exert a protective effect against PD, while evening work and stress may be risk factors for the development of the disease.

Item Type: Article
Uncontrolled Keywords: case-control study, Parkinson’s disease, protective factors, risk factors
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 17 Dec 2015 14:39
Last Modified: 17 Dec 2015 14:39

Actions (login required)

View Item View Item