Depression as a predictor of occupational transition in a multiple sclerosis cohort

Patten, Scott B. and Williams, Jeanne V. A. and Lavorato, Dina H. and Koch, Marcus and Metz, Luanne M. (2013) Depression as a predictor of occupational transition in a multiple sclerosis cohort. Functional Neurology, 28 (4). pp. 275-280. ISSN 1971-3274

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In MS, transitions between working and not-working status may occur in association with depression. This can complicate patients’ ability to promptly obtain disability support due to an expectation that their functioning will improve after the depression resolves, a viewpoint that sees depression assuming a role as a causal determinant of disability. In this study, prospective data were used to model the relationship between depressive symptoms and the transition out of employment. In unadjusted analyses, depression increased the risk of transition to non-working status, HR = 1.7 (95%CI 1.3-2.3). Adjustments for ambulation status, physical and mental quality of life composite scores and fatigue impact attenuated or eliminated the association. While depression commonly occurs around the time of occupational transitions in MS, it does not appear to be an independent or direct cause of such transitions.

Item Type: Article
Uncontrolled Keywords: depression, disability, functional status, multiple sclerosis, occupational status, prospective studies
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 17 Dec 2015 13:04
Last Modified: 17 Dec 2015 13:04

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