Auditory cortical activation and plasticity after cochlear implantation measured by PET using fluorodeoxyglucose

Łukaszewicz-Moszyńska, Zuzanna and Lachowska, Magdalena and Niemczyk, Kazimierz (2014) Auditory cortical activation and plasticity after cochlear implantation measured by PET using fluorodeoxyglucose. Functional Neurology, 29 (2). pp. 121-125. ISSN 1971-3274

article.pdf - Published Version

Download (136kB) | Preview
Official URL:


The purpose of this study was to evaluate possible relationships between duration of cochlear implant use and results of positron emission tomography (PET) measurements in the temporal lobes performed while subjects listened to speech stimuli. Other aspects investigated were whether implantation side impacts significantly on cortical representations of functions related to understanding speech (ipsi- or contralateral to the implanted side) and whether any correlation exists between cortical activation and speech therapy results. Objective cortical responses to acoustic stimulation were measured, using PET, in nine cochlear implant patients (age range: 15 to 50 years). All the patients suffered from bilateral deafness, were right-handed, and had no additional neurological deficits. They underwent PET imaging three times: immediately after the first fitting of the speech processor (activation of the cochlear implant), and one and two years later. A tendency towards increasing levels of activation in areas of the primary and secondary auditory cortex on the left side of the brain was observed. There was no clear effect of the side of implantation (left or right) on the degree of cortical activation in the temporal lobe. However, the PET results showed a correlation between degree of cortical activation and speech therapy results.

Item Type: Article
Uncontrolled Keywords: central nervous system, cochlear implant, neural plasticity, positron emission tomography
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 15 Dec 2015 16:00
Last Modified: 15 Dec 2015 16:00

Actions (login required)

View Item View Item