Effect of PDGF, IGF-1 and PRP on the implant osseointegration. An histological and immunohistochemical study in rabbits

Ortolani, Emanuela and Guerriero, Massimiliano and Coli, Antonella and Di Giannuario, Amalia and Minniti, Gianluca and Polimeni, Antonella (2014) Effect of PDGF, IGF-1 and PRP on the implant osseointegration. An histological and immunohistochemical study in rabbits. Annali di stomatologia, 5 (2). pp. 66-68. ISSN 1971-1441

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Abstract

The ability of platelet-derived growth factor(PDGF), insulin-like growth factor-1 (IGF-1) and platelet-rich plasma (PRP) to increase the rate of osseointegration of endosseous implants and to improve the quality of bone remodeling on the surface of titanium, has been investigated in an experimental intraosseous defect model by an histological and immunohistochemical evaluation. The results from this study demonstrate that rabbits treated with the combination PDGF/IGF-1 showed a higher positive effect on bone regeneration than PRP-treated or controls.

Item Type: Article
Uncontrolled Keywords: PDGF, IGF-1, PRP, growth factors, bone formation, dental implants
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 18 Jan 2016 17:22
Last Modified: 18 Jan 2016 17:22
URI: http://eprints.bice.rm.cnr.it/id/eprint/11438

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