Roura, Eloy and Schneider, Torben and Modat, Marc and Daga, Pankaj and Muhlert, Nils and Chard, Declan and Ourselin, Sebastien and Lladó, Xavier and Gandini Wheeler-Kingshott, Claudia (2015) Multi-channel registration of fractional anisotropy and T1-weighted images in the presence of atrophy: application to multiple sclerosis. Functional Neurology, 30 (4). pp. 245-256. ISSN 1971-3274
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Abstract
Co-registration of structural T1-weighted (T1w) scans and diffusion tensor imaging (DTI)-derived fractional anisotropy (FA) maps to a common space is of particular interest in neuroimaging, as T1w scans can be used for brain segmentation while DTI can provide microstructural tissue information. While the effect of lesions on registration has been tackled and solutions are available, the issue of atrophy is still open to discussion. Multi-channel (MC) registration algorithms have the advantage of maintaining anatomical correspondence between different contrast images after registration to any target space. In this work, we test the performance of an MC registration approach applied to T1w and FA data using simulated brain atrophy images. Experimental results are compared with a standard single-channel registration approach. Multi-channel registration of fractional anisotropy and T1-weighted images in the presence of atrophy: application to multiple sclerosis Both qualitative and quantitative evaluations are presented, showing that the MC approach provides better alignment with the target while maintaining better T1w and FA co-alignment.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Neuroimaging, registration, multiple sclerosis, atrophy |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) > 616.8047548 Sistema Nervoso – Risonanza magnetica nucleare (Classificare qui: Neuroimaging, Neuroimaging funzionale, Cervello - Risonanza magnetica funzionale, Cervello - Risonanza magnetica per immagini) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 24 Sep 2019 14:14 |
| Last Modified: | 24 Sep 2019 14:14 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/12618 |
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