Haemophagocytic Syndrome in a 19-Year-Old Male with Plasmodium falciparum Malaria

Mertens, Rembert and Allard, Sabine D. and Seyler, Lucie and Jochmans, Kristin and Lacor, Patrick (2014) Haemophagocytic Syndrome in a 19-Year-Old Male with Plasmodium falciparum Malaria. European Journal of Case Reports in Internal Medicine, 1 (1). pp. 1-6. ISSN 2284-2594

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Objectives: Infectious agents triggering haemophagocytic lymphohistiocytosis (HLH) primarily involve the herpes virus group. We report a case of HLH precipitated by Plasmodium falciparum. Materials and methods: Clinical and laboratory findings in a patient presenting with fever were collected. After confirmation of acute malaria, anti-malarial treatment was administered. Results: Despite initial favourable evolution, the patient developed fever again together with a worsening of the haematological parameters and increased ferritin levels. A bone marrow biopsy confirmed the diagnosis of HLH. Conclusion: This case illustrates that HLH should be considered in the differential diagnosis of acute malaria in patients with persisting fever and pancytopenia.

Item Type: Article
Uncontrolled Keywords: Plasmodium falciparum, hemophagocytic lymphohistiocytosis
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 07 Sep 2016 15:36
Last Modified: 07 Sep 2016 15:36
URI: http://eprints.bice.rm.cnr.it/id/eprint/14959

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