Can this be considered a Fondaparinux-induced Thrombocytopenia?

Mariotti, Barbara and Rossi, Paolo and Barboni, Enrico (2014) Can this be considered a Fondaparinux-induced Thrombocytopenia? European Journal of Case Reports in Internal Medicine, 1 (1). pp. 1-4. ISSN 2284-2594

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We present a case of an old woman with previously documented heparin-induced thrombocytopenia (HIT), treated with fondaparinux, who presented with thrombocytopenia and venous thrombosis after exposure to a preventive dose of fondaparinux during orthopaedic surgery. Any accidental exposure to heparin was avoided. Other causes of thrombocytopenia were excluded and antigenic tests combined with clinical probability made a diagnosis of HIT likely. Can this be considered a possible case of fondaparinux-related HIT, despite the intense and early decrease in platelets, as usually happens in rapid-onset HIT, and the fact that previous exposure to fondaparinux had occurred 5 months previously?

Item Type: Article
Uncontrolled Keywords: Thrombosis, thrombocitopenia
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 07 Sep 2016 15:45
Last Modified: 07 Sep 2016 15:45

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