Aresmouk, Duaa (2015) Severe Case of Thrombotic Microangiopathy with a Delayed Diagnosis of Atypical Haemolytic Uraemic Syndrome Successfully Managed with Eculizumab. European Journal of Case Reports in Internal Medicine, 2 (2). pp. 1-3. ISSN 2284-2594
|
Text
180-1490-1-PB.pdf - Published Version Download (340kB) | Preview |
Abstract
Objectives: To describe the diagnosis and treatment of a severely ill patient presenting with thrombotic microangiopathy (TMA) of unknown cause. Case presentation: An adult female presented to intensive care with abdominal pain and haemorrhagic shock, requiring reanimation. Results: Features of TMA were present, but initial plasma exchange was ineffective. Treatment with the anti-C5 antibody, eculizumab, improved laboratory parameters and organ function, albeit slowly. Eculizumab remains effective and well tolerated after 30 months of treatment. Conclusion: This case demonstrates the complexities and importance of early identification of atypical haemolytic uraemic syndrome in patients presenting with TMA.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Chronic kidney disease, eculizumab, hemolytic uremic syndrome |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 09 Sep 2016 15:29 |
| Last Modified: | 09 Sep 2016 15:29 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/15019 |
Actions (login required)
 |
View Item |
