Ancient Bruises: a Case of Skin Lesions due to Vitamin C Deficiency

Rao, Dipti and Stolk, Roeland F. and de Blauw, Maaike H. and Hovens, Marcel M.C. and Hassing, Robert-Jan (2015) Ancient Bruises: a Case of Skin Lesions due to Vitamin C Deficiency. European Journal of Case Reports in Internal Medicine, 2 (7). pp. 1-3. ISSN 2284-2594

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Scurvy was a common 18th century disease caused by vitamin C deficiency. It presents with multiple non-specific symptoms and can lead to capillary fragility due to impaired collagen synthesis. We report the case of a 63-year-old woman who presented with fatigue, nausea and progressive skin lesions consisting of multiple ecchymoses on the legs as also described in the diary drawings of a navy doctor in the 19th century. The ascorbic acid level was undetectable low in the patient’s serum. However, treatment with 500 mg ascorbic acid daily dramatically improved the skin lesions within 5 days.

Item Type: Article
Uncontrolled Keywords: Scurvy; ascorbic acid; ecchymosis; psychiatric disease
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.5 Malattie del tegumento, dei peli, delle unghie
Depositing User: Chiara D'Arpa
Date Deposited: 14 Sep 2016 15:06
Last Modified: 14 Sep 2016 15:06

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