Polymyositis and the Spectrum of Scleroderma Disorders

Cochicho, Joana and Madaleno, João and Louro, Emília and Simão, Adélia and Carvalho, Armando (2016) Polymyositis and the Spectrum of Scleroderma Disorders. European Journal of Case Reports in Internal Medicine, 3 (1). pp. 1-3. ISSN 2284-2594

346-2405-1-PB.pdf - Published Version

Download (340kB) | Preview
Official URL: http://ejcrim.com/index.php/EJCRIM/article/view/34...


Polymyositis (PM) is usually associated to other autoimmune or connective tissue diseases. The authors report the case of a 59-year-old man with pulmonary fibrosis, who presented with constitutional symptoms and gradually developed proximal muscle weakness, Raynaud phenomenon, and dysphagia. Besides creatine kinase (CK) elevation, he had positive anti-Polymyositis-Scleromyositis (PM-Scl) and anti-Sjögren's-syndrome A (SSA) antibodies. Nailfold capillaroscopy showed a scleroderma pattern and muscle biopsy revealed necrosis, regeneration of muscle fibers, and inflammatory infiltrate. Prednisolone was started, with great improvement. Taking into account the overlap features between PM and systemic sclerosis sine scleroderma, it is important to closely monitor the patient for signs of pulmonary and cardiac decompensation.

Item Type: Article
Additional Information: L'articolo è stato pubblicato nei Latest online nel 2015
Uncontrolled Keywords: Polymyositis, Systemic sclerosis sine scleroderma, Overlap syndrome
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User: Chiara D'Arpa
Date Deposited: 19 Sep 2016 15:43
Last Modified: 19 Sep 2016 15:43
URI: http://eprints.bice.rm.cnr.it/id/eprint/15106

Actions (login required)

View Item View Item