Left Ventricle Non-Compaction Myocardium and Thrombophilia in a Pregnant Woman

Kochmareva, Elena A. and Kokorin, Valentin A. and Kondrashova, Evgenia A. and Khokhlova, Nadejda V. and Vardanyan, Argishti G. and Kokorin, Ilya A. and Doroshenko, Dmitry A. (2016) Left Ventricle Non-Compaction Myocardium and Thrombophilia in a Pregnant Woman. European Journal of Case Reports in Internal Medicine, 3 (5). pp. 1-4. ISSN 2284-2594

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Non-compaction of the ventricular myocardium (NCM) is a genetic cardiomyopathy usually due to mutationof the G4.5 gene located in the Xq28 chromosomal region. This congenital disorder is characterized by pronounced trabeculations and intertrabecular recesses resulting from abnormal embryogenesis between the fifth and eighth fetal weeks. The reported prevalence in the general population is between 0.014% and 1.3%. The classic triad of complications includes heart failure, ventricular arrhythmias and systemic embolic events, although some patients have an asymptomatic form. NCM is commonly diagnosed by echocardiography, but contrast ventriculography, CT and MRI can also be used. Here we present a case of left ventricle NCM, manifested after respiratory infection, in a pregnant patient with congenital thrombophilia and a history of myocardial infarction.

Item Type: Article
Uncontrolled Keywords: Non-compaction myocardium, pregnancy, heart failure, thrombophilia
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 27 Sep 2016 13:13
Last Modified: 27 Sep 2016 13:13
URI: http://eprints.bice.rm.cnr.it/id/eprint/15172

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