Katsenos, Chrysostomos S. and Moukas, Markos and Baka, Vasiliki and Kafkoula, Eleni and Androulaki, Despoina and Mandragos, Kostas E. (2016) Increasing Skin Pigmentation Following Severe Head Trauma: All That Glitters Is Not Gold! European Journal of Case Reports in Internal Medicine, 3 (6). pp. 1-2. ISSN 2284-2594
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Abstract
We report the case of a 67-year-old man who was admitted to our Intensive Care Unit because of traumatic brain injury. During his prolonged hospitalization, gradual darkening of the skin all over his body was observed. An excess corticotropin (ACTH) production syndrome was considered. The patient’s hormone study showed high levels of ACTH (978 pg/ml) with normal cortisol levels. Extensive clinical and laboratory investigations revealed adenocarcinoma of the colon, which was likely the site of the ectopic ACTH production. This is a very rare manifestation of paraneoplastic syndrome during the course of colon adenocarcinoma. The most important feature of this case report is that this rare syndrome was accidentally discovered, in a patient hospitalized for unrelated reasons, by simple clinical investigation.
| Item Type: | Article |
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| Uncontrolled Keywords: | ACTH; colon adenocarcinoma; ectopic corticotropin production |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 13 Oct 2016 15:00 |
| Last Modified: | 13 Oct 2016 15:00 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/15196 |
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