Still’s-like Disease Induced by Breast Implants in a Middle-Aged Female Health Professional

Lavranos, Giagkos and Kouma, Demetra and Deveros, Antonis and Pigiotou, Georgia and Samanis, Georgios and Zintilis, Chrysostomos (2017) Still’s-like Disease Induced by Breast Implants in a Middle-Aged Female Health Professional. European Journal of Case Reports in Internal Medicine, 4 (1). ISSN 2284-2594

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We report a case of silicone-induced Still’s-like inflammatory syndrome diagnosed after extensive investigation in the department of internal medicine of a secondary hospital. A 45-year-old female healthcare specialist presented with fever, headache, sore throat, myalgia and fatigue. A history of breast augmentation surgery in 2007 was confirmed. Physical examination of the patient was normal while laboratory tests showed a very high white blood cell count. The patient was admitted to hospital due to suspected infection and further laboratory tests were carried out. Inflammatory markers were persistently high despite empirical treatment with doxycycline for possible infection by Rickettsia/Coxiella. As the fever did not resolve and the patient had not improved after more than 3 weeks, the case was investigated as fever of unknown origin. Eventually, the existence of liver granulomas as well as the presence of anti-silicone antibodies confirmed the diagnosis of silicone-induced Still’s-like inflammatory syndrome. In conclusion, this case supports a linkage between silicone breast implants and autoimmune connective tissue diseases.

Item Type: Article
Uncontrolled Keywords: breast implants; fever of unknown origin; silicone; Still disease
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 27 Feb 2017 17:34
Last Modified: 27 Feb 2017 17:34

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