Fundic Gland Polyposis Associated with Proton-Pump Inhibitor Use

Hamada, Kenta and Takeuchi, Yoji and Akasaka, Tomofumi and Iishi, Hiroyasu Fundic Gland Polyposis Associated with Proton-Pump Inhibitor Use. European Journal of Case Reports in Internal Medicine, 4 (5). ISSN 2284-2594


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We describe the case of a man with fundic gland polyposis associated with proton-pump inhibitor (PPI) use. Some investigators have reported an association between long-term PPI use and an increase in the risk of developing fundic gland polyps (FGPs). These FGPs are considered to be reversible on stopping PPI treatment. The current patient had used a PPI for 10 years, resulting in multiple FGPs in his gastric body. However, 6 months after cessation of the PPI, the FGPs had obvously regressed, even though a histamine-2 receptor antagonist had subsequently been prescribed. This case demonstrates a link between PPI treatment and FGPs.

Item Type: Article
Uncontrolled Keywords: Fundic gland polyp; gastric polyp; proton-pump inhibitor
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Michela Donatelli
Date Deposited: 06 Jul 2017 10:26
Last Modified: 06 Jul 2017 10:26

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