A three-dimensional model of a gap junction

Xylouris, Konstantinos and Wittum, G. (2009) A three-dimensional model of a gap junction. Il nuovo cimento C, 32 (1). pp. 231-238. ISSN 1826-9885

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Abstract

Gap junctions are effective electric couplings between neurons and form a very important way of communication between them. Since they can be considered as the points on the neuron’s membrane on which for example dendrites of different cells become one piece, in three dimensions they can be modelled by observing this property in the created geometry. Thus they can be easily made part in an already existing 3-dimensional model for signal propagation on the neuron’s membrane, if the geometries are chosen in such a way that they respect the blending of the membranes. A small network of two cells was created, which blend in their dendrites and a simulation of the three-dimensional model was carried out which reveals the fast transmission of the signal from one cell to the other.

Item Type: Article
Uncontrolled Keywords: Theory, modeling, and simulations ; Action potential propagation and axons ; Synapses: chemical and electrical (gap junctions)
Subjects: 500 Scienze naturali e Matematica > 530 Fisica
Depositing User: Marina Spanti
Date Deposited: 24 Mar 2020 16:33
Last Modified: 24 Mar 2020 16:33
URI: http://eprints.bice.rm.cnr.it/id/eprint/16472

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