A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome

Miyakoshi, Takahiro and Satoh, Mamoru and Nomura, Fumio and Hashimoto, Takao and Aizawa, Toru (2017) A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome. European Journal of Case Reports in Internal Medicine, 4 (7). ISSN 2284-2594

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Objective: To describe hypocalcaemia due to vitamin D deficiency in ‘hikikomori’ syndrome. Materials and methods: A 37-year-old man with ‘hikikomori’ syndrome for a year was admitted with hypocalcaemia (serum ionic calcium 1.17 mmol/l). Serum 1,25(OH)2-vitamin D3 determined by liquid chromatography–tandem mass spectrometry was depressed at 12.1 pg/ml (29.0 pmol/l) and plasma intact PTH elevated at 324 ng/l. Administration of 1 μg/day 1α(OH)-vitamin D3 and 1 g/day calcium lactate for 1 week normalized calcium and PTH, and raised 1,25(OH)2-vitamin D3 to low normal levels. Conclusion: This is the first report of hypocalcaemia due to vitamin D deficiency in a patient with ‘hikikomori’ syndrome.

Item Type: Article
Uncontrolled Keywords: Hikikomori syndrome, Hypocalcemia, Hypovitaminosis D
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 20 Nov 2017 16:19
Last Modified: 20 Nov 2017 16:19
URI: http://eprints.bice.rm.cnr.it/id/eprint/16752

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