Manso, Marta Catarino and Paixão Marques, Diogo and Rocha, Sara L. and Rodeia, Simão C. and Domingos, Raquel (2017) Senile Systemic Amyloidosis: An Underdiagnosed Disease. European Journal of Case Reports in Internal Medicine, 4 (9). ISSN 2284-2594
|
Text
document 10pdf.pdf - Published Version Download (261kB) | Preview |
Abstract
Senile systemic amyloidosis is caused by a non-mutated form of transthyretin with the heart being the major organ involved. This infiltrative cardiomyopathy usually presents as slowly progressive heart failure. An 82-year-old female patient was admitted for newly diagnosed heart failure. A year later she presented with decompensated heart failure and syncope. Inpatient work-up showed persistently elevated troponin and N-terminal-pro BNP levels, rapid progression to severe left ventricular concentric hypertrophy, and sinus pauses on the Holter. Cardiac MRI revealed diffuse late gadolinium enhancement in the left ventricle. The demonstration of amyloid protein with the clinical findings and complementary investigations allowed for the diagnosis of senile systemic amyloidosis
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Cardiac amyloidosis, senile systemic amyloidosis, amyloidosis, heart failure with preserved ejection fraction |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 26 Jan 2018 10:11 |
| Last Modified: | 26 Jan 2018 10:11 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/17009 |
Actions (login required)
 |
View Item |
