Cryptococcal Meningitis in a HIV-Negative Patient

Barreiros, Cátia and Meireles-Brandão, Lúcia and Silva, Duarte and Rodrigues, Carmélia and Guerra, Diana (2017) Cryptococcal Meningitis in a HIV-Negative Patient. European Journal of Case Reports in Internal Medicine, 5 (2). ISSN 2284-2594

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Sarcoidosis is a risk factor for the development of cryptococcal infection due to dysfunction at T-cell level. Its rarity may, however, delay diagnosis and treatment. We describe the case of a 60-year-old man, diagnosed with sarcoidosis since 1999. He had never received systemic immunomodulatory therapy, such as corticosteroid therapy. In 2012, he was diagnosed with pulmonary cryptococcosis and treated with fluconazole. In April 2013, he presented with symptoms compatible with central nervous system (CNS) infection, namely, Cryptococcus neoformans meningitis. He was treated with amphotericin B, followed by fluconazole. The clinical outcome was favourable.

Item Type: Article
Uncontrolled Keywords: Sarcoidosis, Cryptococcus neoformans, meningitis, HIV negative
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 18 May 2018 14:25
Last Modified: 18 May 2018 14:25

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