Torti, Andrea (2012) Study of magnetic domain wall trapping forces on superparamagnetic beads for on chip biological manipulation. Il nuovo cimento C, 35 (5). pp. 171-178. ISSN 1826-9885
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Abstract
The manipulation of biological molecules and single cells on a surface is of fundamental importance for the development of novel magnetic lab-on-chip tools for biological and medical applications. Geometrically constrained magnetic domain walls (DWs) in permalloy nano- and micro-conduits can be manipulated precisely by applying weak external magnetic fields. The inhomogeneous magnetic stray field generated by a DW can capture magnetic beads in solution. The use of the highly controllable motion of these DWs allows the handling of functionalized magnetic particle and labeled single yeast cells within a microfluidics cell. In this paper we study both via simulations and experimentally the DWs micromagnetic configurations and the force exerted on a superparamagnetic bead. These results show the versatility of domain wall conduits in manipulating different biological entities in lab-on-chip devices. Networks of conduits containing bifurcations, curved portions and DW-AMR sensors can enlarge the range of practical applications.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Micromagnetic simulations ; Domain walls and domain structure ; Nanotechnologies - applications in biology |
| Subjects: | 500 Scienze naturali e Matematica > 530 Fisica |
| Depositing User: | Marina Spanti |
| Date Deposited: | 24 Apr 2020 16:12 |
| Last Modified: | 24 Apr 2020 16:12 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/17945 |
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