The ‘SILENT Alarm’: When History Taking Reveals a Potentially Fatal Toxicity

Anani, Sapir and Goldhaber, Gal and Wasserstrum, Yishay and Dagan, Amir and Segal, Gad (2018) The ‘SILENT Alarm’: When History Taking Reveals a Potentially Fatal Toxicity. European Journal of Case Reports in Internal Medicine, 5 (6). ISSN 2284-2594

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Introduction: The combination of acute/sub-acute neurological and metabolic derangements should always raise the suspicion of toxicity, either endogenous or exogenous. The adverse effects of psychiatric medications are especially difficult to determine since the psychiatric background of patients is often inaccessible. Clinical Presentation: A 66-year-old man presented to the emergency department with dysarthria and uncontrolled tremor, rapidly deteriorating into a complex of severe neurological and metabolic derangements. Only after repeated attempts to take a thorough history was lithium toxicity identified. Conclusion: Thorough, comprehensive history taking, including chronic medications and their substitutes, is essential and lifesaving when potentially lethal medications are involved.

Item Type: Article
Uncontrolled Keywords: Lithium, SILENT syndrome, history taking, bipolar disorder, drug toxicity
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 08 Aug 2018 10:51
Last Modified: 08 Aug 2018 10:51

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