Primary Hepatic Diffuse Large B-cell Lymphoma Mimicking Acute Fulminant Hepatitis

El Murr, Toni and El Nouwar, Ricardo (2018) Primary Hepatic Diffuse Large B-cell Lymphoma Mimicking Acute Fulminant Hepatitis. European Journal of Case Reports in Internal Medicine, 5 (6). ISSN 2284-2594

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Abstract

Primary hepatic lymphoma (PHL) is a rare variant of non-Hodgkin's lymphoma. Diffuse hepatic involvement is uncommon and therefore presentation as progressive hepatitis or acute fulminant hepatic failure is rare. Acute onset of signs and symptoms can mimic a variety of infectious and inflammatory disorders, thus delaying the diagnosis. A high index of suspicion and liver biopsy early in the course of liver dysfunction may establish the diagnosis and allow rapid initiation of chemotherapy to prevent a fatal outcome. In this report, we describe a rare case of fulminant primary hepatic diffuse large B-cell lymphoma in a 55-year-old woman who died 2 weeks after admission, before the initiation of chemotherapy.

Item Type: Article
Uncontrolled Keywords: Primary hepatic lymphoma, non-Hodgkin’s lymphoma, diffuse large B-cell lymphoma, cute fulminant hepatitis
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 08 Aug 2018 11:20
Last Modified: 08 Aug 2018 11:20
URI: http://eprints.bice.rm.cnr.it/id/eprint/18164

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