An Unusual Case of Primary Retroperitoneal Germ Cell Tumour in a Young Man

Serpa, Maria João Raposo Linhares and Franco, Susana and Repolho, Diana and Branco, Francisco and Gramaça, João and Júnior, José Ferreira (2018) An Unusual Case of Primary Retroperitoneal Germ Cell Tumour in a Young Man. European Journal of Case Reports in Internal Medicine, 5 (7). ISSN 2284-2594

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Abstract

Some 2–5% of germ cell tumours are of extragonadal origin, with a retroperitoneal location being very rare. The majority of retroperitoneal germ cell tumours have metastasized from a testicular tumour. These tumours are diagnosed incidentally or symptomatically and nearly all present with high alpha-fetoprotein and lactate dehydrogenase levels. We describe the unusual case of a 31-year-old man with a yolk-sac, retroperitoneal germ cell tumour, with normal serum alpha-fetoprotein and lactate dehydrogenase levels, which has not previously been described. A testicular tumour was excluded by physical examination and additional tests. Our diagnosis was based on a high level of suspicion and histopathological results. As far as we know, this is the first case described with these characteristics.

Item Type: Article
Uncontrolled Keywords: Neoplasms, germ cell and embryonal, male germ cell tumor, extragonadal, non-seminomatous, yolk-sac tumour, alpha-fetoproteins
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 27 Aug 2018 11:16
Last Modified: 27 Aug 2018 11:16
URI: http://eprints.bice.rm.cnr.it/id/eprint/18186

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