A Rare Case of Bilateral Proptosis

Serodio, Joao Fernandes and Jonet, Marta and Trindade, Miguel and Coutinho, Inês and Favas, Catarina (2018) A Rare Case of Bilateral Proptosis. European Journal of Case Reports in Internal Medicine, 5 (11). ISSN 2284-2594

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Abstract

A 65-year-old man presented with a 2-year history of severe bilateral proptosis, palpable lymphadenopathy and moderate hepatosplenomegaly. A blood test was positive for hepatitis C infection. CT showed palpebral infiltrative lesions with regional progression through the temporal and masticatory spaces to the pharynx and hypopharynx causing almost complete airway obstruction. A palpebral biopsy was consistent with low-grade Bcl-2+ extra-nodal MALT non-Hodgkin B-cell lymphoma. The patient received six cycles of rituximab-based chemotherapy with clinical remission at 9-month follow-up. Bilateral proptosis is a rare presentation of several diseases. When brain CT excludes cavernous sinus pathology, thyroid ophthalmopathy or haematological malignancy should be considered.

Item Type: Article
Uncontrolled Keywords: Palpebral MALT B-cell lymphoma, hepatitis C infection
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Greta Di Blasio
Date Deposited: 11 Jun 2019 10:28
Last Modified: 11 Jun 2019 10:28
URI: http://eprints.bice.rm.cnr.it/id/eprint/18803

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