Wolf, Frieda and Glick, Karina and Elias, Mazen and Mader, Reuven (2018) Portal Vein Thrombosis and Thrombocytopenia in Eosinophilic Granulomatosis with Polyangiitis: A Paradox? European Journal of Case Reports in Internal Medicine, 5 (11). ISSN 2284-2594
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Abstract
A 36-year-old woman with eosinophilic granulomatosis with polyangiitis (EGPA) presented with necrotic skin lesions and pulmonary infiltrates. There was eosinophilic vasculitis on skin biopsy, and substantial tissue eosinophilia in her bone marrow. She had unexplained worsening thrombocytopenia, which prompted a thrombophilia work-up. However, abnormalities in liver enzymes led to the extraordinary finding of portal vein thrombosis. Thrombocytopenia resolved with treatment with low molecular weight heparin. This case highlights the risk of hypercoagulability in eosinophilia specifically, and in EGPA. We suggest that thrombosis should be ruled out in all cases of EGPA.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Portal vein thrombosis, hypercoagulability, eosinophilia, EGPA |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Greta Di Blasio |
| Date Deposited: | 11 Jun 2019 10:27 |
| Last Modified: | 11 Jun 2019 10:27 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/18804 |
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