The Perfect Storm: A Case of Non-Uremic Calciphylaxis

Barbosa, Manuel Martins and Araújo, Elsa and Pereira, Marta Matos and Mendes, Tiago Manuel (2019) The Perfect Storm: A Case of Non-Uremic Calciphylaxis. European Journal of Case Reports in Internal Medicine, 6 (4). ISSN 2284-2594

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Calciphylaxis is a severe condition associated with chronic kidney disease. We describe a rare case of non-uremic calciphylaxis in a 79-year-old woman with prosthetic aortic and mitral valves, chronic kidney disease and anaemia, who presented with painful skin lesions on her left leg. She was taking warfarin, calcium and iron supplements, and had been recently diagnosed with oligoarthritis and started on prednisolone, all factors associated with calciphylaxis. Despite treatment, the lesions rapidly progressed to large ulceration and sepsis, and pain management was challenging. Calciphylaxis was confirmed following a second skin biopsy but the patient died from septic shock and multi-organ failure. This case highlights the challenges associated with the diagnosis and treatment of calciphylaxis despite a high level of suspicion.

Item Type: Article
Uncontrolled Keywords: Non-uremic calciphylaxis, calciphylaxis lesions, wound care, CKD complications
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 10 Jun 2019 14:44
Last Modified: 10 Jun 2019 14:44

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