Gitelman Syndrome Diagnosed in a Woman in the Second Trimester of Pregnancy

Çetik, Sila and Basaran, Nursel Calik and Ozisik, Lale and Oz, Serife Gul and Arici, Mustafa (2019) Gitelman Syndrome Diagnosed in a Woman in the Second Trimester of Pregnancy. European Journal of Case Reports in Internal Medicine, 6 (4). ISSN 2284-2594

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Gitelman syndrome is a rare renal tubule disease characterized by hypokalaemia, metabolic alkalosis, hypomagnesaemia, hypocalciuria and normal blood pressure. It shows autosomal recessive inheritance and is usually not diagnosed until late childhood or adulthood. We report the case of 34-year-old woman who at 21 weeks of pregnancy was admitted to the gynaecology department for abdominal pain, muscle cramps and weakness. Routine blood tests showed hypokalaemia (2.32 mEq/l), hypomagnesaemia (1.18 mEq/l), compensated metabolic alkalosis (pH 7.439, bicarbonate 26.1 mmol/l), increased urinary magnesium excretion (140.25 mg/day, normal range 73–122 mg/day) and reduced urinary calcium excretion (49.25 mg/day, normal range 100–250 mg/day). In light of these findings, the patient was diagnosed with Gitelman syndrome and optimum potassium and magnesium levels were maintained with oral supplements.

Item Type: Article
Uncontrolled Keywords: Gitelman syndrome, pregnancy, hypokalemia, hypocalciuria
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 10 Jun 2019 14:45
Last Modified: 10 Jun 2019 14:45

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