Kong Cardoso, B. and Martins, M. and Martins Farinha, S. and Viseu, R. and Tomaz, E. and Inácio, F. (2019) Late-Onset Rash from Irbesartan: An Immunological Reaction. European Journal of Case Reports in Internal Medicine, 6 (6). ISSN 2284-2594
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Abstract
Cutaneous delayed reactions to antihypertensive drugs have been described in a limited number of case reports but the mechanisms remain mostly unknown. We report the case of a 60-year-old female patient with a 3-week history of an itchy erythematous maculopapular eruption. Although the patient was polymedicated, irbesartan was the most likely culprit. Patch tests and a lymphocyte transformation test to irbesartan were both positive, which was useful for diagnosis and suggested an immunological reaction. No new lesions appeared after irbesartan was stopped or after the introduction of candesartan. Despite its similar chemical structure, candesartan may be tried in patients allergic to irbesartan.
| Item Type: | Article |
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| Uncontrolled Keywords: | Irbesartan allergy, maculopapular rash, patch tests, lymphocyte transformation test, drug reaction |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Lorenzo Sgro |
| Date Deposited: | 28 Feb 2020 15:27 |
| Last Modified: | 28 Feb 2020 15:27 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/19481 |
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