Pinto, Sara and Naia, Leonor and Ferreira, Gisela and Eulálio, Margarida (2019) T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Challenging Diagnosis. European Journal of Case Reports in Internal Medicine, 6 (8). ISSN 2284-2594
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Abstract
Epstein-Barr virus (EBV) is a double-stranded virus that shows tropism for B-cell lymphocytes. EBV-infected patients usually present with tonsillitis/pharyngitis, cervical lymphadenopathy and fever, but an atypical presentation can mimic lymphoproliferative disease. We present the case of a 77-year-old woman with asthenia, fever, oral ulcers and peripheral lymphadenopathy. After extensive evaluation, including anatomopathological and immunocytochemical examination of excisional lymph node biopsy samples, it was still not clear whether the patient had EBV infection or diffuse large B-cell lymphoma. In this case report, the authors describe how it can be difficult to differentiate between two different, although related, entities, making diagnosis of lymphoma highly challenging.
| Item Type: | Article |
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| Uncontrolled Keywords: | Diffuse large B-cell lymphoma, Epstein-Barr virus infection, herpes simplex infection |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 18 Nov 2020 20:43 |
| Last Modified: | 18 Nov 2020 20:43 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/19502 |
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