Costa, Mylene and Greenfield, Helena and Pereira, Ricardo and Chuva, Teresa and Henrique, Rui and Cunha, Cátia (2019) A Rare Case of Renal AA Amyloidosis Secondary to Sjogren’s Syndrome. European Journal of Case Reports in Internal Medicine, 6 (9). ISSN 2284-2594
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Abstract
AA amyloidosis is a rare complication of chronic inflammatory disorders and has been associated with rheumatoid arthritis and ankylosing spondylitis. We present a case of AA amyloidosis secondary to Sjogren’s syndrome (SS). A 79-year-old woman presented with rapidly progressive renal failure and complaints of asthenia, anorexia and generalized oedema. She had severe renal failure (creatinine 6.0 mg/dl), with microscopic haematuria, nephrotic proteinuria and low serum albumin levels, and an increased erythrocyte sedimentation rate. Serum protein electrophoresis revealed a peak in the gamma globulin zone. The patient was started on haemodialysis and corticosteroids. Clinical results showed the patient met the diagnostic criteria for primary SS, and neoplastic haematological disease was excluded. Renal biopsy revealed a diagnosis of AA amyloidosis. Renal AA amyloidosis is a rare condition in patients with primary SS. However, in patients with proteinuria and/or renal failure, it should be included in the differential diagnosis and a renal biopsy should be performed.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Sjogren's syndrome, AA amyloidosis, renal amyloidosis, renal biopsy |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 18 Nov 2020 20:54 |
| Last Modified: | 18 Nov 2020 20:55 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/19519 |
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