Khan, Rashid and Ajaz, Yasmeen and Pandey, Anoop Kumar and AlSaffar, Khalid and Narayanan, Sunil Roy Thottuvelil (2019) Cerebral Venous Thrombosis and Acute Pulmonary Embolism following Varicella Infection. European Journal of Case Reports in Internal Medicine, 6 (10). ISSN 2284-2594
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Abstract
Varicella infection is caused by varicella-zoster virus (VZV) and commonly presents as a self-limiting skin manifestation in children. VZV also causes cerebral arterial vasculopathy and antibody-mediated hypercoagulable states leading to thrombotic complications in children, although there are very few such reports in adults. Postulated causal factors include vasculitis, direct endothelial damage, or acquired protein S deficiency secondary to molecular mimicry. These induced autoantibodies to protein S could lead to acquired protein S deficiency and produce a hypercoagulable state causing venous sinus thrombosis. Here we report the case of a 26-year-old man who presented with cortical venous sinus thrombosis and acute pulmonary embolism following varicella infection. Both conditions responded to anticoagulation treatment.
| Item Type: | Article |
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| Uncontrolled Keywords: | Venous thrombosis, pulmonary embolism, varicella infection, protein S deficiency, hypercoagulable state |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 19 Nov 2020 09:08 |
| Last Modified: | 19 Nov 2020 09:08 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/19522 |
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