Diagnostic Pitfalls in a Man with Systemic Lupus Erythematous

Dan Gheorghe, Andrei Cristian and Hodorogea, Andreea Simona and Georgescu, Cristina Elena and Ciobanu, Ana and Nanea, Ioan Tiberiu and Gheorghe, Gabriela Silvia (2019) Diagnostic Pitfalls in a Man with Systemic Lupus Erythematous. European Journal of Case Reports in Internal Medicine, 6 (11). ISSN 2284-2594

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Systemic lupus erythematosus (SLE) is a chronic multi-systemic immune-mediated disease with confusing symptoms and delayed diagnosis. We report the case of a 32-year-old man with a persistent Venereal Disease Research Laboratory (VDRL)-positive reaction treated for syphilis 5 years previously, who was admitted for rash, weight loss, pancytopenia, inflammatory syndrome, and an important spontaneous prolongation of activated partial thromboplastin time (aPTT). Antiphospholipid antibodies were identified in the patient and he was diagnosed with SLE. The unrecognized false positive VDRL reaction and the delayed diagnosis of SLE were harmful as the patient had developed renal and cardiac complications by the time of diagnosis.

Item Type: Article
Uncontrolled Keywords: Systemic lupus erythematous, antiphospholipid antibodies, aPTT
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 19 Nov 2020 09:33
Last Modified: 19 Nov 2020 09:33
URI: http://eprints.bice.rm.cnr.it/id/eprint/19584

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