Pituitary Apoplexy Following Systemic Anticoagulation

Mairos dos Santos, Ana Rita and Bello, Carlos and Sousa, Alice and Duarte, João and Campos, Luís (2019) Pituitary Apoplexy Following Systemic Anticoagulation. European Journal of Case Reports in Internal Medicine, 6 (12). ISSN 2284-2594

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Abstract

Pituitary apoplexy is a rare medico-surgical emergency that stems from an acute expansion of a pituitary adenoma from infarction or haemorrhage and where the treatment strategy is still controversial. Clinical presentation is highly variable and a high index of suspicion is needed to make the diagnosis. Furthermore, in less than half of cases, a precipitating event is identified. We report a case of a 74-year-old female who, after introduction of anticoagulation for pulmonary thromboembolism, presented with pituitary apoplexy heralded by acute adrenal insufficiency, headaches, visual symptoms and hypogonadotropic hypogonadism. Timely initiation of corticosteroids was crucial, and after stabilisation, a conservative treatment strategy was favoured with good long-term prognosis. Long-term follow-up of pituitary function also revealed new growth hormone deficiency.

Item Type: Article
Uncontrolled Keywords: Pituitary apoplexy, hypopituitarism, adrenal insufficiency, low molecular weight heparin, headache
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 19 Nov 2020 09:38
Last Modified: 19 Nov 2020 09:38
URI: http://eprints.bice.rm.cnr.it/id/eprint/19613

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