Vaz, Joana Alves and Frada, Lilia and Soares, Maria Manuela and Mello e Silva, Alberto (2019) POEMS Syndrome: an Atypical Presentation with Chronic Diarrhoea and Asthenia. European Journal of Case Reports in Internal Medicine, 7 (1). ISSN 2284-2594
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Abstract
POEMS syndrome is a rare paraneoplastic condition associated with polyneuropathy, organomegaly, monoclonal gammopathy, endocrine and skin changes. We report a case of a man with Castleman disease and monoclonal gammopathy, with a history of chronic diarrhoea and asthenia. Gastrointestinal involvement in POEMS syndrome is not frequently referred to in the literature and its physiopathology is not fully understood. Diagnostic criteria were met during hospitalization but considering the patient’s overall health condition, therapeutic options were limited. Current treatment for POEMS syndrome depends on the management of the underlying plasma cell disorder. This report outlines the importance of a thorough review of systems and a physical examination to allow an attempted diagnosis and appropriate treatment.
| Item Type: | Article |
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| Uncontrolled Keywords: | POEMS syndrome, chronic diarrhoea, polyneuropathy |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 16 Nov 2020 21:11 |
| Last Modified: | 16 Nov 2020 21:11 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/19762 |
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