Freitas, Sara and Marques, Joana and Grilo, Ana and Gomes, Rodolfo and Gonçalves, Fernando (2020) Behçet’s Disease and Tuberculosis: A Complex Relationship. European Journal of Case Reports in Internal Medicine, 7 (2). ISSN 2284-2594
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Abstract
Behçet’s disease (BD) is a systemic vasculitis characterized by recurrent orogenital ulceration and several systemic manifestations (such as gastrointestinal involvement, vascular disease or arthritis). The pathogenesis is still unknown but the trigger role of certain pathogens such as Mycobacterium tuberculosis is well documented. Furthermore, patients with BD are more susceptible to tuberculosis due to immunity defects. Here, we describe the case of a 70-year-old woman with a history of recurrent oral aphthae and inflammatory arthritis presenting with extensive thrombosis of left upper limb major veins, a positive HLA B51 genotype and colon ulceration; hence, BD diagnosis was made after excluding other causes. Simultaneously, the patient had cutaneous abscesses not associated with immunosuppressive therapy with continuous development, and after recurrent negative tuberculosis work-up, M. tuberculosis was isolated in an abscess culture.
| Item Type: | Article |
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| Uncontrolled Keywords: | Cutaneous tuberculosis, Behçet’s disease, venous thrombosis |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 19 Nov 2020 09:56 |
| Last Modified: | 19 Nov 2020 09:56 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/19839 |
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