Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis

Ferreira, Sofia and Lemos, Cláudia and Caldeira, Mónica and Homem da Costa, Miguel and Brazão, Maria Luz and Aveiro, Fernando (2020) Isolated Congenital Asplenia in an Asymptomatic Patient: A Very Rare Diagnosis. European Journal of Case Reports in Internal Medicine, 7 (4). ISSN 2284-2594

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Isolated congenital asplenia is a rare condition that mostly manifests in the early years, usually due to fatal systemic infections. In this paper, however, we present a case of a 36-year-old asymptomatic patient who was referred for suspected hyposplenism, with no history of splenectomy. There were no significant changes on physical examination. Blood analysis revealed leukocytosis and thrombocytosis as well as moderate anisopoikilocytosis and red blood cells with Howell–Jolly bodies. No spleen or other malformations were identified on imaging. Individuals with isolated congenital asplenia have an increased susceptibility to invasive infections and sepsis, with rapid clinical decline and a high mortality rate despite treatment.

Item Type: Article
Uncontrolled Keywords: Isolated congenital asplenia, hyposplenism, sepsis
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 19 Nov 2020 10:16
Last Modified: 19 Nov 2020 10:16

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