Insulinoma Identified in Puerperium: Association with Pregnancy and Literature Review

Orabona, Rossana and Zanardini, Cristina and Lojacono, Andrea and Zatti, Sonia and Cappelli, Carlo and Tiberio, Guido and Villanacci, Vincenzo and Sartori, Enrico (2020) Insulinoma Identified in Puerperium: Association with Pregnancy and Literature Review. European Journal of Case Reports in Internal Medicine, 7 (4). ISSN 2284-2594

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Postpartum hypoglycemia in non-diabetic women is a rare condition. We report the case of a 34-year-old woman who experienced neuroglycopenia 2 days after delivery. Corresponding to severe hypoglycemia, we found inappropriately elevated insulin and C-peptide levels. Following magnetic resonance imaging a lesion of 10x8 mm was detected in the head of the pancreas. An ultrasound-guided fine needle aspiration of the mass confirmed the diagnostic suspicion of a pancreatic neuroendocrine tumor. Complete surgical enucleation of the insulinoma resulted in immediate and permanent resolution of the hypoglycemia. The postoperative course was uneventful. Histopathological and immunohistochemical analyses were consistent with insulinoma. The diagnostic approach to postpartum hypoglycemia represents a challenge for multidisciplinary teamwork.

Item Type: Article
Uncontrolled Keywords: Neuroendocrine tumor, hypoglycemia, pregnancy, postpartum, insulinoma, puerperium, neuroglycopenia
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 24 Nov 2020 13:54
Last Modified: 24 Nov 2020 13:54

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