Cannabis Hyperemesis Syndrome: A Still Under-Recognized Syndrome

Hassene, Attout and Sofia, Amichi and Françoise, Josse and Vincent, Appavoupoule and Andrey, Randriajohany and Yogananda, Thirapathi (2020) Cannabis Hyperemesis Syndrome: A Still Under-Recognized Syndrome. European Journal of Case Reports in Internal Medicine, 7 (5). ISSN 2284-2594

document (2).pdf - Published Version

Download (185kB) | Preview
Official URL:


Cannabis is one of the most widely used illicit drugs in the world. Its use is associated with several short- and long-term side-effects such as changes in mood, impaired memory, impaired attention, depression and anxiety, and it is correlated with schizophrenia. Cannabinoid hyperemesis syndrome (CHS) is characterized by chronic cannabis use, cyclic intractable nausea and vomiting, and compulsive hot bathing. Patients are typically diagnosed with CHS only after multiple medical evaluations. Recent research has identified type 1 cannabinoid receptors in the intestinal nerve plexus that have an inhibitory effect on gastrointestinal motility. This effect may explain hyperemesis in cannabis users. The thermoregulatory role of endocannabinoids may be responsible for compulsive hot bathing. We describe the cases of two young men seeking repeated emergency room care with recurrent nausea and vomiting. Abstinence from cannabis led to resolution of vomiting symptoms and abdominal pain.

Item Type: Article
Uncontrolled Keywords: Cannabis, hyperemesis, hot bathing
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 24 Nov 2020 14:04
Last Modified: 24 Nov 2020 14:04

Actions (login required)

View Item View Item