Panzetta, Valeria and Pugliese, Mariagabriella and di Gennaro, Gioia and Federico, Costabile and Arrichiello, Cecilia (2018) X-rays affect cytoskeleton assembly and nanoparticle uptake: Preliminary results. Il nuovo cimento C, 41 (6). pp. 1-8. ISSN 1826-9885
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Abstract
Alterations of the cytoskeleton are commonly associated with tumor genesis and cancer progression. For this reason, the characterization of cytoskeletonassociated functions and properties is important to optimize the outcomes to classical and more recent therapeutic approaches, such as chemotherapy, radiotherapy and cancer nanomedicine. In such context, this work investigated the synergy between cancer nanomedicine and radiotherapy. In particular, the effects over time (24 and 48h) of two different doses of X-rays (2 and 10Gy) on spreading area, morphological parameters and the internalization mechanism of carboxylated nanoparticles in mammary epithelial cells and mammary adenocarcinoma cells were investigated.
| Item Type: | Article |
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| Subjects: | 500 Scienze naturali e Matematica > 530 Fisica |
| Depositing User: | Marina Spanti |
| Date Deposited: | 27 Nov 2020 09:36 |
| Last Modified: | 27 Nov 2020 09:36 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/20339 |
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