Imaging is believing: The future of human total-body molecular imaging starts now

Majewski, Stanislaw (2020) Imaging is believing: The future of human total-body molecular imaging starts now. Il nuovo cimento C, 43 (1). pp. 1-15. ISSN 1826-9885

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Abstract

Explorer brings revolution to medical imaging. The wealth of molecular/functional information provided by a single scan is overwhelming. Beyond the obvious issues of how to store and analyze this vast amount of data, and how to fuse the PET images from the almost 200 cm long total-body PET imager with MRI images, the imaging scientists work on improving spatiotemporal resolution of the scanner. But how can we obtain better spatial and time (time of flight) resolutions at the same time? Efforts to push timing resolution down to 50 ps and potentially even down to 10 ps were initiated. While attaining ∼ 1 mm resolution in the totalbody Explorer imager is not immediately practically possible or even justifiable, due to other limiting factors such as large amount of recorded coincident events (“statistics”) necessary to produce good quality ∼ 1 mm resolution images in the human body and not just as before in the small animal body, one of the high-resolution scenarios is to imagine and start planning magnifying attachments-inserts to the Explorer scanner and a dedicated very high-performing (∼ 1 mm resolution, 100 ps or better TOF resolution and ∼30% efficiency) compact brain imager. This (Explorer + Brain) Tandem PET scanner may be closer to the ideal optimal human PET imager, if there is small interference between the two imager components to image body and brain, respectively. Other options such as 100 cm long extended Torso Explorer plus Brain Imager are also being discussed.

Item Type: Article
Subjects: 500 Scienze naturali e Matematica > 530 Fisica
Depositing User: Marina Spanti
Date Deposited: 29 Jan 2021 15:20
Last Modified: 29 Jan 2021 15:20
URI: http://eprints.bice.rm.cnr.it/id/eprint/20716

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