Kalogeropoulos, Charalampos I and Papathanasiou, Konstantinos A and Tsagkaraki, Ismini and Giannopoulos, Georgios and Bamias, Aristotelis and Boutati, Eleni I (2020) A Case of Meningococcal and HSV-2 Meningitis in a Patient Being Treated with Ustekinumab for Pityriasis Rubra Pilaris. European Journal of Case Reports in Internal Medicine, 7 (8). pp. 1-5. ISSN ISSN: 2284-2594
|
Text
1615-Article Text-13609-1-10-20200520.pdf - Published Version Download (457kB) | Preview |
Abstract
Pityriasis rubra pilaris (PRP) is a rare chronic inflammatory papulosquamous dermatosis affecting both adults and children. Six subtypes of PRP have been described. Recently, the management of PRP with biologic immunosuppressive agents regularly used in psoriasis has been supported by several case reports and series. Ustekinumab is an anti-IL12/23 IgG1 kappa human monoclonal antibody. It has been approved for the treatment of Crohn’s disease, plaque psoriasis, psoriatic arthritis and ulcerative colitis. It has also been reported to be effective as an off-label treatment for PRP. Current data are equivocal regarding infectious disease risk with ustekinumab administration. We describe a case of meningococcal and HSV-2 infection of the central nervous system in a patient being treated with ustekinumab for PRP.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Pityriasis rubra pilaris (PRP), ustekinumab, meningococcal meningitis |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 14 Dec 2021 15:13 |
| Last Modified: | 14 Dec 2021 15:13 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/20977 |
Actions (login required)
 |
View Item |
