Mitra, Asis and Ray, Saswati (2020) High-Titre ANA Positivity in NAFLD: An Uncommon Presentation of a Common Disease. European Journal of Case Reports in Internal Medicine, 7 (9). pp. 1-3. ISSN ISSN: 2284-2594
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Abstract
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and has emerged as a serious public health challenge. About 20% of NAFLD patients may have low titres (<1:320) of antinuclear antibodies (ANA). However, we describe a patient with NAFLD whose ANA titre was high (>1:320) on presentation. After 3 months of diet, exercise and vitamin E supplementation,the patient was symptomatically better but her ANA titre had increased (>1:640). Her liver biopsy showed features of NAFLD with minimal fibrosis. High-titre ANA (>1:320) positivity is rare. Our patient showed a progressive rise in ANA titre from >1:320 to >1:640 within 3 months even though she was improving and histology showed minimal fibrosis.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Antinuclear antibody, non-alcoholic fatty liver disease, autoimmune hepatitis, liver biopsy |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 15 Dec 2021 12:37 |
| Last Modified: | 15 Dec 2021 12:37 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/20985 |
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