Costantini, Luisa and Marando, Marco and Gianella, Pietro (2020) Long-Term GeneXpert Positivity after Treatmentfor Pulmonary Tuberculosis. European Journal of Case Reports in Internal Medicine, 7 (10). pp. 1-3. ISSN ISSN: 2284-2594
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Abstract
Tuberculosis (TB) is a cause of ill health and death worldwide. Since 2010, the diagnostic process has strongly relied on GeneXpert assays on biological specimens. Xpert MTB/RIF is an automated nucleic acid amplification test (NAAT) for Mycobacterium tuberculosis and rifampicin resistance, endorsed by the World Health Organization and the US Food and Drug Administration. Xpert is used in many countries as the initial diagnostic test for tuberculosis. Nevertheless, the reliability of GeneXpert positive tests in patients with a history of TB is largely unknown, due to possible false-positive results (i.e., GeneXpert-positive but culture-negative patients). We present a case report of a patient with a history of pulmonary TB, who was GeneXpert positive but culture negative on bronchoalveolar lavage 22 months after completion of appropriate antitubercular therapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Tuberculosis, TB, GeneXpert, retested patients, false positives |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 15 Dec 2021 13:40 |
| Last Modified: | 15 Dec 2021 13:40 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21020 |
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