Boon Tay, Hui and Angkodjojo, Stanley and En Amos Tay, Zhi and Hoon Tan, Puay and Denise Tan, Yan (2020) Angioimmunoblastic T-cell Lymphoma: A Mimic for Lupus. European Journal of Case Reports in Internal Medicine, 7 (10). pp. 1-4. ISSN ISSN: 2284-2594
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Abstract
New-onset systemic lupus erythematosus (SLE) is uncommon in elderly patients. We report the case of a 71-year-old woman who was diagnosed with SLE based on clinical manifestations of fever, alopecia, bicytopenia, hepatomegaly, lymphadenopathy, glomerulonephritis, positive antinuclear antibody (ANA) and anti-double stranded DNA (anti-dsDNA) antibody. Renal biopsy was consistent with lupus nephritis and excision biopsy of a right inguinal lymph node was initially reported as having features of reactive hyperplasia. However, a more careful review of the lymph node biopsy subsequently confirmed a concurrent angioimmunoblastic T-cell lymphoma. This case illustrates the importance of investigating secondary causes and possible alternative diagnoses in patients who present with atypical features of connective tissue disease, and the challenges in diagnosing a rare form of lymphoma.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Elderly-onset systemic lupus erythematosus, lupus nephritis, angioimmunoblastic T-cell lymphoma |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 15 Dec 2021 13:43 |
| Last Modified: | 15 Dec 2021 13:43 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21026 |
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