Infectious Mononucleosis Resulting in Acute Necrotizing Mediastinitis: A Case Report and Literature Review

Van Noten, Héloïse and Markowicz, Samuel and Cappeliez, Serge and Cherifi, Soraya (2020) Infectious Mononucleosis Resulting in Acute Necrotizing Mediastinitis: A Case Report and Literature Review. European Journal of Case Reports in Internal Medicine, 7 (11). pp. 1-4. ISSN ISSN: 2284-2594

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Abstract

The serological prevalence of Epstein-Barr virus (EBV) among young adults exceeds 90% worldwide. Even though EBV primary infection is usually benign, severe complications can occur in adolescents and young adults and so the disease must be promptly diagnosed. The development of an oropharyngeal abscess leading to a descending necrotizing mediastinitis (DNM) is exceptional and potentially lethal, so early diagnosis with a CT scan, appropriate antibiotics and surgery are essential. The authors present a case where DNM was associated with reactive hemophagocytic syndrome as a result of infectious mononucleosis, as well as a review of similar cases in the English literature.

Item Type: Article
Uncontrolled Keywords: Epstein-Barr virus, infectious mononucleosis, descending necrotizing mediastinitis, retropharyngeal abscess, reactive hemophagocytic syndrome
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 15 Dec 2021 14:09
Last Modified: 15 Dec 2021 14:09
URI: http://eprints.bice.rm.cnr.it/id/eprint/21043

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