Aveiro, Marcelo and Ferreira, Gisela and Matias, Carla and Oliveira, Ana and Rodrigues, Tatiana (2020) Hard-To-Treat Idiopathic Refractory Autoimmune Haemolytic Anaemia with Reticulocytopenia. European Journal of Case Reports in Internal Medicine, 7 (12). pp. 1-3. ISSN ISSN: 2284-2594
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Abstract
Autoimmune haemolytic anaemia (AIHA) is an uncommon condition characterized by increased destruction of erythrocytes associated with reticulocytosis in the great majority of cases. We present the case of a 68-year-old woman with jaundice and malaise. Investigation revealed AIHA with reticulocytopenia. The patient failed to respond to prednisolone or to rituximab. Azathioprine and epoetin beta were subsequently started, the prednisolone dose was increased, and the patient began to respond after 1 month. In AIHA, reticulocytopenia is a very rare presentation and a sign of great severity and poor outcome. The scarcity of therapeutic options in refractory cases poses a major challenge for physicians.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Haemolytic anaemia, reticulocytopenia, azathioprine |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 20 Dec 2021 14:10 |
| Last Modified: | 20 Dec 2021 14:10 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21067 |
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