Reda Belkhribchia, Mohamed and Moukhlis, Sara and Bentaoune, Tarik and Chourkani, Najat and Zaidani, Mohamed and Karkouri, Mehdi (2020) Skeletal Myopathy as the Initial Manifestation of Light Chain Multiple Myeloma. European Journal of Case Reports in Internal Medicine, 7 (12). pp. 1-4. ISSN ISSN: 2284-2594
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Abstract
Monoclonal gammopathies due to plasma cell dyscrasias can cause various rare neuromuscular disorders. The peripheral nervous system is most commonly affected, while muscle diseases associated with monoclonal gammopathies are rare. Skeletal myopathy, as a manifestation in the context of multiple myeloma, is extremely uncommon and is usually the result of immunoglobulin light chain (AL) amyloidosis deposits in the muscles. Here we present an atypical case of a patient with generalized myopathy as the presenting manifestation of light chain multiple myeloma. Interestingly, muscle involvement in our case was not the consequence of AL amyloidosis deposits but rather due to non-amyloid light chain deposition disease associated with light chain multiple myeloma.
| Item Type: | Article |
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| Uncontrolled Keywords: | Light chain deposition disease, skeletal myopathy, light chain multiple myeloma, monoclonal immunoglobulin deposition disease, chemotherapy |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 20 Dec 2021 14:21 |
| Last Modified: | 20 Dec 2021 14:21 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21081 |
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